Reagents
| Reagent | Type | Created | Author | Actions | |
|---|---|---|---|---|---|
Necdin-null miceMice with a gene-tergeted deletion of Necdin are available from the Jackson Laboratories. See http://jaxmice.jax.org/strain/009089.html. B6.129S1(Cg)-Ndntm2Stw/J, Stock number 009089 Repository- Live
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Model | July 10, 2013 | rwevrick | ||
Magel2-null miceMice gene targeted for Magel2 are available from the Jackson Laboratories. See http://jaxmice.jax.org/strain/009062.html. Strain Name: C57BL/6-Magel2tm1Stw/J, Stock Number: 009062, Availability: Cryopreserved - Ready for recovery |
Model | July 10, 2013 | rwevrick | ||
PWS-IC<del> miceWhen females heterozygous for the PWS-ICdel mutation are bred with wildtype males, the resulting offspring are viable and fertile as adults. In contrast, paternal transmission of the PWS-ICdel mutation results in neonatal lethality between 1-7 days of age (failure to [...] |
Model | August 6, 2013 | msasner | ||
PWS-IC<flox6kb> miceThese PWS-ICflox6kb mice may be useful in generating conditional mutations for studying the role of Snrpn and the temporal and developmental requirements of the Prader-Willi imprinting center. Mice homozygous for this PWS-ICflox6kb allele are viable and fertile, [...] |
Model | August 6, 2013 | msasner | ||
Nes-cre miceWhen crossed to male mice carrying the PWS-IC<flox6kb> allele (see JAX Stock No.018395), Cre recombinase expression in brain precursors cells starting at E10.5 results in a growth retardation, but is not lethal. For more information [...] |
Model | August 6, 2013 | msasner | ||
CMV-cre miceWhen crossed to male mice carrying the PWS-IC<flox6kb> allele (see JAX Stock No. 018395), widespread Cre recombinase expression prior to implantation results in postnatal lethality. For more information [...] |
Model | August 6, 2013 | msasner | ||
Expression constructs for necdin and Magel2A variety of plasmids are available in which either necdin or Magel2 cDNA is cloned into vectors for expression in yeast, bacteria, or mammalian cells. Contact RachelWevrick@ualberta.ca for information. |
Vector | July 10, 2013 | rwevrick |